The World Health Organization recommends vaccinating in those who are at high risk of the disease including children who live in areas where it is common.Three doses are given over a one-month period.
Immunity following a course of doses is typically long lasting.Additional doses are not typically needed except in those at very high risk.Following administration of a booster dose, one study found 97% of immuno-competent individuals demonstrate protective levels of neutralizing antibodies at 10 years.
In addition to these developments, newer and less expensive purified chicken embryo cell vaccine, and purified Vero cell rabies vaccine are now available. The purified Vero cell rabies vaccine uses the attenuated Wistar strain of the rabies virus, and uses the Vero cell line as its host.
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